In this article we explore the opportunity to create spaces that specifically promote the well-being of transgender adolescents and young adults. While many of the approaches designed to improve social spaces for lesbian, gay, and bisexual (LGB) youth will also support transgender youth, policies and practices may not apply to, or actively include, these adolescents who face unique needs and opportunities. This article describes family, school, and community contexts linked to the well-being of transgender adolescents, and presents data from focus groups with transgender youth conducted at sexual minority youth community centers.