Mamow-Sha-way-gi-kay-win: North-South Partnership for Children represents a coalition of individuals and organizations from southern Ontario who have partnered with First Nations Chiefs, community leaders, Elders, youth and community members from 30 remote northern communities. The collective goal of the Partnership is to learn from one another while addressing the needs of First Nations communities.This community assessment and mobilization process uses the social determinants of health in the context of northern First Nations realities as a framework for understanding community wellness. Children’s mental health, and specifically youth suicide, is viewed as a product of various interactions within and among these factors. It is proposed that through Mamow Ki- ken-da-ma-win, meaningful immediate and long-term outcomes to urgent conditions and challenges can be achieved.